WebCerebellar degeneration is a disorder that affects nerves in the back of your brain. It can lead to balance issues or difficulty with speech and eyesight. Cerebellar degeneration can be the result of several health conditions like alcohol use disorder or cancer. Appointments 866.588.2264 Appointments & Locations Request an Appointment WebAug 1, 2024 · In addition, phenytoin can cause cerebellar syndrome, which manifests itself as ataxia, nystagmus, hand tremor, and diplopia. These manifestations of cerebellar syndrome are dependent on phenytoin dose and blood concentration; tremor occurs at an average plasma concentration of 20 μg/mL, and ataxia occurs at 30 μg/mL.
Dilantin Side Effects: Cerebellar Atrophy and More
WebFeb 17, 2024 · It is a sequela of chronic alcohol use or malnutrition. Terminology Alcoholic cerebellar degeneration has also been described in the literature as a lcohol-related cerebellar degeneration, alcohol-induced cerebellar degeneration and nutritional cerebellar degeneration 1,2. Epidemiology The prevalence is estimated at 12 – 27% from autopsies 2. WebApr 11, 2024 · We compared this case clinicopathologically with other diseases with cortical cerebellar atrophy; alcoholic cerebellar degeneration, phenytoin intoxication, neuroleptic malignant syndrome, and ... 鯱もなか本店
Phenytoin/sodium-valproate SpringerLink
WebPhenytoin is an effective anticonvulsant for focal epilepsy. Its use can be associated with long-term adverse effects including cerebellar ataxia. Whilst phenytoin is toxic to Purkinje cells in vitro; the clinical and radiological phenotype and mechanism of cerebellar degeneration in vivo remain unclear. WebCerebellar Atrophy or Cerebral atrophy (atrophy of the brain) has been linked to Dilantin (Phenytoin), medications commonly used to treat seizures and epilepsy as well as depression and arrhythmias. Dilantin (Phenytoin) is an anticonvulsant that can be considered the grandfather of all epilepsy medications. WebApr 15, 2024 · Serum phenytoin level was 42 µg/mL and serum valproate level was 64 µg/mL. MRI of the brain and spine showed calcified granuloma (right frontal lobe) and … 鯱もなか総本店