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Ligong chen and oct1

NettetOrganic cation transporter 1 (OCT1; SLC22A1) seems to play a role in the efficacy and disposition of the widely used antidiabetic drug metformin. Genetic variants in OCT1 … NettetThe effect of OCT1 on picoplatin pharmacokinetics and antitumor efficacy was determined using OCT knockout mice and HEK293 xenografts stably expressing OCT1. The …

Likun GONG Chinese Academy of Sciences, Beijing CAS

NettetOCT1 in hepatic steatosis and thiamine disposition. OCT1 in hepatic steatosis and thiamine disposition Cell Cycle. 2015;14(3):283-4. doi: … Nettet15. jun. 2024 · MOF-derived catalysts with nickel nanoparticles (NPs) uniformly embedded in nitrogen doped carbon shells were developed by pyrolysis of nickel-based metal–organic frameworks (MOFs), in which amino groups were introduced to act as the nitrogen source and possible anchoring sites for Ni NPs. The resulting mate safety features in cars 2016 https://ashleywebbyoga.com

OCT1 is a high-capacity thiamine transporter that regulates …

Nettet16. apr. 2024 · Our study provides evidence that imbalances in a micronutrient, vitamin B1 (thiamine), can serve as an etiological cause of lipid and glucose disorders and … NettetOCT1 (assay ID: Hs00427550_m1), OCT2 (assay ID: Hs00533907_m1), OCT3 (assay ID: Hs01009568_m1), and human glyceraldehyde-3-phosphate dehydrogenase (assay ID: Hs99999905_m1). Quantitative RT-PCR was carried out in 96-well reaction plates in a volume of 10 ml using the TaqMan Fast Universal Master Mix (Applied Biosystems, … Nettet8. jul. 2014 · Organic cation transporter 1, OCT1 (SLC22A1), is the major hepatic uptake transporter for metformin, the most prescribed antidiabetic drug. ... Ligong Chen 1 , … thewpblog

Likun GONG Chinese Academy of Sciences, Beijing CAS

Category:Ligong Chen - School of Public Health UAB

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Ligong chen and oct1

OCT1 is a high-capacity thiamine transporter that regulates …

Nettet1. okt. 2010 · Ligong Chen, Miho Takizawa, Eugene Chen, ... cence using GFP chimeras of OCT1 and its variants (Chen et al., 2006). Stably transfected HEK293 cells were harvested and washed. NettetHere we show that Oct1 deficiency results in reduced hepatic steatosis and phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase (ACC). …

Ligong chen and oct1

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NettetDr. Ligong Chen obtained his BS from Nankai University in Chemistry in 1997. He completed his PhD from University of California at Berkeley and postdoctoral training … NettetYing Chen, 1 Shuanglian Li, 1 Chaline Brown, 1 Stephen Cheatham, 1 Richard A. Castro, 1 Maya K. Leabman, 1 Thomas J. Urban, 1 Ligong Chen, 1 Sook Wah Yee, 1 Ji Ha Choi, 1 Yong Huang, 1 Claire M. Brett, 2 Esteban G. Burchard, 1 and Kathleen M. Giacomini 1 ... We observed that OCT1 genotype had no significant effects on metformin …

Nettet10. okt. 2016 · The resulting cellulose aerogels were characterized using various techniques. It was found that the CMC/CNF aerogel exhibited a honeycomb structure, and thus possessed anisotropic properties. Moreover, the fully biobased crosslinked organic aerogel possessed excellent mechanical properties based on both compression and … Nettet通过对IN690合金进行的固溶处理试验和压缩试验,研究了其合金晶粒组织和碳化物的变化规律以及碳化物对组织均匀性的影响.结果表明:晶粒组织随固溶温度的升高而增大,碳化物含量随温度升高而逐渐减小.当碳化物完全溶解时,晶粒会急剧长大.因而碳化物在晶界处有钉扎作用,限制晶粒的快速长大,对 ...

NettetOrganic cation transporter 1 (OCT1;SLC22A1) seems to play a role in the efficacy and disposition of the widely used antidia- betic drug metformin. Genetic variants in OCT1 have been identified largely in European populations. Metformin is in- creasingly being used in Asian populations where the incidence of type 2 diabetes (T2D) is on the rise. NettetLigong Chen1,2, Sook Wah Yee3, and Kathleen M Giacomini3,4,* 1Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University; ... Comment on: Chen L, et al.OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin. Proc Natl Acad SciUSA 2014; 111(27) ...

Nettet27. mar. 2024 · Adoptive cell-transfer (ACT) therapy, which involves the ex vivo expansion and reinfusion of tumor-reactive T cells such as tumor-infiltrating lymphocytes (TILs) and, genetically-retargeted T cells with conventional T-cell receptors (TCRs) or chimeric antigen receptors (CARs), is emerging as a potential curative treatment for patients with …

NettetThe article was published on 2006-01-01. It has received 4 citation(s) till now. The article focuses on the topic(s): Mandelic acid & Adsorption. the wp engine teamNettetSook Wah Yee 1,2, Ligong Chen 1,2 & Kathleen M Giacomini 1 1Department of Bioengineering and Therapeutic Sciences, ... Oct1-transfected A29 and A38 cells showed significantly lower the w parisNettetGiving. Learn about the UAB School of Public Health's efforts during the Covid-19 Pandemic. Home. About. People. Staff. Ligong Chen. thewpf.netNettetLigong Chen Lucia Lazorova [...] Per Artursson Common genetic variants of the liver-specific human organic cation transporter 1 (OCT1; SLC22A1) have reduced transport capacity for substrates... thewp-groupNettet24. jun. 2014 · Organic cation transporter 1, OCT1 (SLC22A1), is the major hepatic uptake transporter for metformin, the most prescribed antidiabetic drug. ... Ligong Chen. … thewpf.orgNettet11. apr. 2024 · 2213888. First Published: 15 January 2024. A versatile protocol for the horizontally-oriented growth of submillimeter-long organic crystalline nanowires on flexible polymer films is proposed. Accordingly, a large number of organic nanowires are integrated into flexible photodetectors directly on their growth substrate. the w perimeter hotelNettet20. okt. 2012 · A hemicyanine dye with imidazole as the acceptor was designed and prepared as a chemosensor for fluoride anions. The experimental results demonstrated that it is a fluorometric probe for fluoride anion with good sensitivity and high selectivity. This probe showed obvious changes in UV–Vis absorption and fluorescence spectra in … the wp-config.php file isn’t included in mac