WebAbstract Assembly of cilia and flagella requires intraflagellar transport (IFT), a highly regulated kinesin-based transport system that moves cargo from the basal body to the tip of flagella [1]. The recruitment of IFT components to basal bodies is a function of flagellar length, with increased recruitment in rapidly growing short flagella [2]. Web22 nov. 2024 · Removing IFT proteins has proven to be a more specific mechanism for disrupting primary cilia since Kif3a was found to have non-ciliary effects on Wnt …
Direct imaging of intraflagellar-transport turnarounds reveals that ...
Web10 apr. 2024 · Here, we show that in the common butterfly Pieris brassicae, the spermatocyte cilia are exceptionally long: about 40 μm compared to less than 1 μm in … Web6 jul. 2024 · The Golgi apparatus (GA) is essential for intracellular sorting, trafficking and the targeting of proteins to specific cellular compartments. Anatomically, the GA spreads all over the cell but is also particularly enriched close to the base of the primary cilium. This peculiar organelle protrudes at the surface of almost all cells and fulfills many cellular functions, in … お得意様 納品できない
Architecture of the IFT ciliary trafficking machinery and interplay ...
Web19 mrt. 2024 · Cilia and flagella are microtubule doublet based organelles found across the eukaryotic tree of life. Their very high aspect ratio and crowded interior are unfavourable … Web2 dec. 2024 · Intraflagellar transport (IFT) trains are massive molecular machines that traffic proteins between cilia and the cell body. Each IFT train is a dynamic polymer of two … WebAuthor: Peter Satir Publisher: Humana ISBN: 9781493981397 Format: PDF, Mobi Release: 2024-06-09 Language: en View This volume is the result of an explosion of molecular-based research on Cilia, which began with the discovery of the universality of intraflagellar transport (IFT) and ciliary genomics/proteomics. passaruota clio 4